The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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5mg Mounjaro Reviews: How It Compares to Wegovy
5mg Mounjaro reviews from people considering weight loss treatment often compare it to Wegovy, as both are prescription-only GLP-1-based injections available in the UK. However, they work differently and produced different results in clinical trials. Understanding the evidence behind each medication, rather than relying solely on reviews, helps you and your GP make an informed decision about which might suit your health needs. Both require a clinical assessment before prescription.
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Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Clinical Trial Data: SURMOUNT vs STEP Studies
When evaluating 5mg Mounjaro reviews, it's helpful to consider the clinical trial evidence. Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist — meaning it activates two hormone pathways, not one. In the SURMOUNT-1 trial, participants taking 5mg Mounjaro lost an average of approximately 15% of their body weight over 72 weeks alongside a reduced-calorie diet and increased physical activity.
Wegovy (semaglutide) is a GLP-1-only agonist. In the STEP-1 clinical trial, participants achieved an average weight loss of approximately 14.9% on the maximum 2.4mg dose. The 5mg Mounjaro dose falls partway through the Mounjaro titration schedule, so direct numerical comparison is less straightforward.
Important context: these are clinical trial averages — individual results vary significantly, and results were achieved with diet and activity changes, not medication alone.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
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Side Effects and Suitability: Individual Prescriber Assessment
5mg Mounjaro reviews often mention nausea, diarrhoea, and stomach discomfort — these are common early side effects of both Mounjaro and Wegovy. The incidence and severity vary between individuals. Mounjaro's dual mechanism may produce a different side effect profile than Wegovy's single GLP-1 pathway, though both can cause similar gastrointestinal effects.
The choice between Mounjaro and Wegovy cannot be made purely from reviews; it requires a clinical assessment with a UK-licensed prescriber. They will consider your medical history, other medications, BMI, and eligibility criteria. Use our free GLP-1 weight loss calculator to understand potential outcomes at different doses, and discuss the trial evidence with your prescriber to determine which medication is most suitable for you.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Is 5mg Mounjaro better than Wegovy based on reviews?
Reviews are individual experiences and cannot be generalised. Clinical trial data shows Mounjaro (5mg and above) and Wegovy (at maximum dose 2.4mg) both produce significant weight loss, but through different mechanisms. Your prescriber will assess which is more suitable for your health profile, not which has better reviews.
What makes Mounjaro different from Wegovy?
Mounjaro is a dual GIP and GLP-1 receptor agonist; Wegovy is GLP-1-only. This means Mounjaro activates two natural hormone pathways, which may explain different efficacy and side effect patterns in trials. Both are prescription-only and require clinical assessment.
Do 5mg Mounjaro reviews mention different side effects than Wegovy?
Both medications commonly cause nausea, diarrhoea, and stomach issues. Individual tolerance varies. Some reviewers report these effects diminish over time; others report differences between the two medications. Side effect profiles should be discussed with your prescriber, not predicted from reviews.
Can I choose between Mounjaro and Wegovy based on trial results?
Trial data informs prescriber decisions but cannot be applied directly to you. Factors including your eligibility, medical history, previous medication responses, and clinical assessment determine which is prescribed. Your GP or licensed prescriber will make this decision.
How can I check if I'm eligible for either 5mg Mounjaro or Wegovy?
Both require a BMI of 30kg/m² or above, or 27–29.9kg/m² with weight-related health conditions. Use our free BMI calculator to check your BMI, then discuss eligibility with your GP or licensed prescriber via a clinical assessment.
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