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Used by Mounjaro & Wegovy patients across the UK

The UK's most complete GLP-1 guide

Every Question Answered. Every Side Effect Explained.

  • How GLP-1 medications work
  • Mounjaro vs Wegovy compared
  • Injection instructions
  • Side effects & solutions
  • What to eat on treatment
  • FAQs answered
Get the guide + free tracker — £1.99 →

Free tracker included with every download this week

GLP-1 Medication Guide — 11 chapters, 100+ pages, NHS-aligned with free 52-week weight loss tracker calendar
Free · Instant · No sign-up required

Do Digestive Enzymes Help With Weight Loss?

Digestive enzymes are popular in weight management circles, but the evidence for their effectiveness in helping you lose weight is limited. Digestive enzymes break down food into smaller molecules, but they don't directly reduce appetite or increase calorie burning. While they may support better digestion in some people, most clinical research shows they have minimal impact on weight loss outcomes. For effective weight management in the UK, evidence-based approaches like dietary changes, physical activity, and NHS-approved prescription weight loss medication have proven far stronger results.

10,000+ calculations today · NHS-aligned thresholds · 100% free

26%of UK adults are living with obesityNHS Digital, 2023
64%of adults in England are overweight or obeseHealth Survey for England
£6.5bnannual cost of obesity to the NHSPublic Health England
4.7Mpeople in England eligible for weight loss drugsNICE estimates, 2024

Calculate Your BMI Instantly

Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.

What Is BMI and Why Does It Matter?

Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).

While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.

Below 18.5Underweight
18.5 – 24.9Healthy
25 – 29.9Overweight
30+Obese

The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.

How Digestive Enzymes Work and Why They Don't Drive Weight Loss

Digestive enzymes like protease, lipase, and amylase break down proteins, fats, and carbohydrates in the stomach and small intestine, helping your body absorb nutrients more efficiently. However, this improved digestion doesn't directly translate to weight loss. Your body already produces sufficient digestive enzymes naturally—supplementing with additional enzymes rarely enhances this process in healthy people.

  • Enzymes may ease bloating or indigestion in people with enzyme deficiencies, but this is different from weight loss
  • No enzyme supplement can reduce appetite or increase your metabolic rate significantly
  • Weight loss depends on creating a calorie deficit—consuming fewer calories than you burn
  • Enzymes don't block calorie absorption or suppress hunger hormones

If you're struggling with indigestion alongside weight management, your GP can assess whether a genuine enzyme deficiency exists. For most people seeking weight loss in the UK, evidence-based methods—like adjusting your diet for weight management and increasing physical activity—offer far better outcomes than enzyme supplements alone.

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How It Works

Three simple steps to understand your weight and take action.

1Check Your BMI

Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.

2Explore Your Options

If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.

3Track Your Progress

Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.

Free Weight Loss Tools & Guides

Everything you need to understand your weight, explore medication options, and track your progress — completely free.

What Actually Works for Weight Loss in the UK

The NHS weight loss guidance emphasises sustainable dietary changes, increased physical activity, and behavioural support as the foundation for weight management. Our free GLP-1 weight loss calculator can help you explore projected outcomes with evidence-based prescription weight loss medication if you're eligible. For adults with a BMI of 30 or above—or 27 or above with weight-related health conditions—prescription options like Mounjaro and Wegovy have demonstrated clinical effectiveness through rigorous trials.

If digestion is a concern alongside weight loss, discuss this with your GP, who can rule out underlying conditions. Digestive enzymes may provide modest relief for bloating but shouldn't be relied upon as a weight loss strategy. Use our BMI calculator to understand your current status, then explore evidence-based options suited to your individual circumstances.

Mounjaro (Tirzepatide)
  • Dual GIP/GLP-1 receptor agonist
  • Up to 22.5% body weight loss (SURMOUNT-1)
  • Weekly injection, dose escalation over 20+ weeks
  • Available via private prescription in the UK
  • Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
Read our full Mounjaro guide →
Wegovy (Semaglutide)
  • GLP-1 receptor agonist
  • Up to 15–17% body weight loss (STEP trials)
  • Weekly injection, 5-step dose escalation
  • NHS & private prescription available
  • Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Read our full Wegovy guide →

Mounjaro vs Wegovy: Head-to-Head

A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.

FeatureMounjaroWegovy
Drug classDual GIP/GLP-1 agonistGLP-1 agonist
Active ingredientTirzepatideSemaglutide
Avg. weight loss15–22.5%12–17%
Key trialSURMOUNT-1 (2022)STEP 1 (2021)
Max dose15 mg weekly2.4 mg weekly
Escalation period20–32 weeks16–20 weeks
AdministrationWeekly injection (pen)Weekly injection (pen)
NHS availabilityPrivate prescription onlyNHS & private
Approx. private cost£150–£250/month£150–£300/month
Common side effectsNausea, diarrhoea, constipationNausea, vomiting, diarrhoea

Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.

Am I Eligible for Weight Loss Medication?

In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.

Standard eligibility
  • BMI of 30 or above (obese)
  • Age 18 or over
  • No contraindicated conditions
  • Committed to lifestyle changes
With comorbidities
  • BMI of 27 or above
  • Plus type 2 diabetes
  • Or high blood pressure
  • Or obstructive sleep apnoea

Use our BMI calculator to check whether your BMI falls within the eligible range.

How We Built These Tools

Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.

All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.

We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.

Frequently Asked Questions

Common questions about BMI, weight loss medications, and our free UK tools.

Do digestive enzyme supplements actually help you lose weight?

No, digestive enzymes do not directly cause weight loss. While they may improve digestion in people with enzyme deficiencies, they don't reduce appetite, block calorie absorption, or increase metabolic rate. Weight loss requires a calorie deficit, which enzymes alone cannot create. They're not an effective weight loss tool for most people.

Can digestive enzymes reduce bloating and help with weight management?

Digestive enzymes may reduce bloating in some people, which can make you feel more comfortable, but this is not weight loss. Bloating relief might encourage better dietary habits, but the enzymes themselves don't reduce body fat. If bloating is persistent, consult your GP to rule out underlying digestive conditions.

What's the difference between Wegovy and digestive enzyme supplements for weight loss?

Wegovy (semaglutide) is a prescription-only GLP-1 medication clinically proven to help weight loss by reducing appetite and supporting feeling fuller after smaller meals. Digestive enzymes only break down food and have minimal impact on weight. In STEP clinical trials, Wegovy helped people lose around 15% of body weight—far more effective than enzymes for weight management UK goals.

Are there any risks to taking digestive enzyme supplements?

Digestive enzymes are generally safe for most people, but they're unnecessary for those with normal enzyme production. Potential side effects include stomach discomfort or allergic reactions in sensitive individuals. Always inform your GP if you're taking supplements, especially if you have existing digestive conditions or take other medications.

What's the best approach to weight loss if digestive enzymes don't work?

Evidence-based weight loss methods include: a reduced-calorie diet (approximately 500 kcal deficit daily for 0.5 kg weekly loss), increased physical activity, and behavioural support through NHS weight management services. For eligible adults, prescription weight loss medication through NHS specialist services or private prescription offers proven effectiveness alongside lifestyle changes.

Ready to take control of your weight loss journey?

Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.

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