The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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Food Noise on Mounjaro vs Wegovy — How They Compare
Food noise — the constant mental chatter about food, cravings, and thinking about eating — is a key reason people consider prescription weight loss injections. Both Mounjaro (tirzepatide) and Wegovy (semaglutide) may help reduce food noise, but they work slightly differently. This guide explains the differences between these two GLP-1 and dual-mechanism medications, how they compare in clinical trials, and which prescription might suit you based on your individual health. Always consult your GP or a licensed prescriber for personalised advice.
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Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
How Mounjaro and Wegovy Reduce Food Noise — The Mechanism Difference
Wegovy (semaglutide) is a GLP-1 receptor agonist only — it activates a single hormone pathway in the brain and gut that signals fullness and reduces appetite. In the STEP clinical trials, Wegovy helped participants achieve an average weight loss of approximately 14.9% body weight at the maximum 2.4 mg dose over 68 weeks.
Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist — it activates two hormone pathways simultaneously. The SURMOUNT-1 trial showed average weight loss of approximately 20.9% body weight at the maximum 15 mg dose. The dual mechanism may provide a stronger appetite suppression effect, which some users report as more significant food noise reduction.
- Wegovy: single pathway activation, gradual dose escalation (0.25 mg to 2.4 mg over 16+ weeks)
- Mounjaro: dual pathway activation, slower dose titration (2.5 mg to 15 mg over 20+ weeks)
- Both are once-weekly injections available via UK prescription
- Individual results vary — mechanism difference does not assures superior outcomes for every person
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
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Choosing Between Mounjaro and Wegovy — Suitability and NHS Access
Both medications require a clinical assessment from a UK-licensed prescriber or NHS specialist weight management service before prescription. Eligibility depends on your BMI and any weight-related health conditions — your GP can advise whether you meet NHS criteria. Try our GLP-1 weight loss calculator above to explore how either medication might support your weight loss goals based on different dose levels. Access in the UK is available through NHS specialist services (with longer waiting times in many regions) or private online prescription services. A prescriber will assess which medication suits your individual health profile, medical history, and any contraindications — not all medications are suitable for all people.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Does Mounjaro reduce food noise more than Wegovy?
Clinical trials show Mounjaro may produce stronger appetite suppression on average due to its dual GIP+GLP-1 mechanism, compared to Wegovy's GLP-1 mechanism alone. However, individual responses vary significantly — some people experience substantial food noise reduction on either medication. Your prescriber will help assess which suits you.
Which is faster acting — Mounjaro or Wegovy?
Both are once-weekly injections. Mounjaro has a slower dose titration (starting at 2.5 mg, increasing every 4 weeks) while Wegovy escalates more quickly (starting at 0.25 mg). Neither is "faster" — they follow different escalation schedules to achieve therapeutic dose.
Can I switch from Wegovy to Mounjaro if food noise isn't reduced enough?
Possibly, but only with prescriber guidance. Any medication switch requires clinical reassessment. Approximate dose equivalences exist (e.g., Wegovy 2.4 mg ≈ Mounjaro 15 mg), but switching must be managed by your prescriber — never switch without consultation.
Is Mounjaro available on the NHS for food noise reduction?
Mounjaro is NICE-approved for NHS specialist weight management services, but access varies significantly by region and waiting times can be lengthy. Private prescription is available through licensed UK prescribers. Your GP can advise on NHS eligibility and local access options.
What side effects affect food noise perception?
Both medications commonly cause nausea, especially in the first 4–8 weeks. This can suppress appetite and reduce food noise but may also make eating difficult. Other side effects include constipation and diarrhoea, which don't directly affect food noise perception. Side effects usually improve over time as your body adjusts to each dose.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.