The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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How To Increase Weight Loss On Mounjaro
Weight loss on Mounjaro depends on several factors, including your current dose, lifestyle changes, and individual response to the medication. If you're not seeing the weight loss results you expected, your prescriber may increase your Mounjaro dose, recommend dietary adjustments, or suggest additional physical activity. This guide explains how dose titration works, compares Mounjaro with Wegovy (semaglutide), and outlines what you can do to support your weight loss journey. Always discuss any changes with your GP or prescriber before making adjustments.
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Calculate Your BMI Instantly
Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Mounjaro Dose Titration And Weight Loss Results
Mounjaro is prescribed in a step-wise dose escalation schedule, starting at 2.5 mg and increasing every 4 weeks up to a maximum of 15 mg weekly. Clinical trial data from SURMOUNT-1 showed that higher doses correlated with greater average weight loss: approximately 15% body weight at 5 mg, 19.5% at 10 mg, and 20.9% at 15 mg over 72 weeks.
However, individual results vary significantly. Some people achieve substantial weight loss at lower doses, while others may benefit from reaching the maximum 15 mg dose. Your prescriber will assess your response at each dose level and recommend escalation based on your progress and tolerability. This Mounjaro dose titration process typically takes 5–6 months to reach a maintenance dose.
- Each dose increment lasts a minimum of 4 weeks
- Weight loss may plateau temporarily during dose transitions
- Gastrointestinal side effects often improve over time as your body adjusts
- Your prescriber may pause escalation if side effects are significant
Our GLP-1 weight loss calculator can help you estimate projected results at different doses, though actual outcomes depend on your individual circumstances and adherence to lifestyle changes.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
Mounjaro Vs Wegovy: Mechanism And Weight Loss Differences
The key difference is the mechanism: Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist, whilst Wegovy (semaglutide) activates GLP-1 only. This dual action in Mounjaro may explain why clinical trials showed slightly higher average weight loss compared to Wegovy, though both are effective prescription weight loss injections available in the UK.
SURMOUNT-1 (Mounjaro) showed average weight loss of 20.9% at maximum dose; STEP-1 (Wegovy) showed approximately 14.9%. However, these trials used different populations and follow-up periods—direct individual comparison is not reliable. Your prescriber will assess which medication is most suitable based on your health profile, other medications, and medical history. Both require clinical assessment before prescription and should be combined with reduced-calorie diet and increased physical activity for optimal results. Individual response varies considerably regardless of which medication you use.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Can I increase my Mounjaro dose faster to lose more weight?
No. Mounjaro must be increased in 2.5 mg increments every 4 weeks minimum. Faster escalation increases risk of gastrointestinal side effects and does not improve weight loss outcomes. Your prescriber follows safety guidelines for dose titration. If you're concerned about progress, discuss this with your GP or prescriber rather than self-adjusting.
What lifestyle changes increase weight loss on Mounjaro?
Mounjaro works alongside a reduced-calorie diet and increased physical activity. The NHS recommends creating a calorie deficit of around 500 kcal per day for approximately 0.5 kg weekly loss. Include both cardiovascular exercise and strength training. Keep a food diary and use our progress tracker to monitor your journey—these practical steps significantly enhance medication effectiveness.
Is Wegovy better than Mounjaro for weight loss?
Both medications are effective. Clinical trials show Mounjaro achieved slightly higher average weight loss, but individual results vary substantially. Neither is objectively "better"—suitability depends on your personal health profile, medical history, and prescriber assessment. Your GP will recommend the most appropriate weekly weight loss injection for you following clinical evaluation.
How long does it take to see weight loss on Mounjaro?
Most people notice some weight loss within the first 4 weeks, though initial loss may include water weight. Significant, sustained weight loss typically becomes evident after 8–12 weeks as your dose increases. Weight loss continues gradually over months. Consistency with diet, exercise, and taking your injections as prescribed is essential for results.
What if I'm not losing weight on maximum Mounjaro dose?
If you're on 15 mg weekly without adequate weight loss after 6 months, discuss this with your prescriber. They may recommend reviewing your diet and activity levels, checking for medical conditions affecting weight loss, or considering whether a different medication might suit you better. Never stop medication without guidance—consult your GP first.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.