The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
Free tracker included with every download this week
How to Wean Off Mounjaro Safely
Stopping Mounjaro (tirzepatide) requires careful medical planning rather than stopping suddenly. If you're thinking about coming off Mounjaro, your GP or prescriber will create a step-down plan tailored to your individual health needs. This guide explains the NHS approach to safely discontinuing Mounjaro, what to expect when weaning off, and why medical supervision is essential throughout the process.
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Calculate Your BMI Instantly
Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
NHS Approach to Stopping Mounjaro
The NHS recommends gradual dose reduction rather than abrupt cessation. This is especially important because stopping suddenly can trigger rapid weight regain, rebound appetite, and blood sugar fluctuations in people with type 2 diabetes. Your GP or specialist should discuss your reasons for stopping — whether health concerns, side effects, or personal choice — and develop a tailored weaning schedule.
- Typical weaning involves stepping down to lower Mounjaro doses over 4–12 weeks, depending on your current dose
- Your prescriber may recommend holding at a lower maintenance dose (e.g., 2.5 mg or 5 mg) before stopping entirely
- Monitoring of weight, appetite, and blood sugar levels continues throughout the process
- If you have type 2 diabetes, your diabetes medication may need adjusting as your weight or glucose control changes
Never adjust or stop Mounjaro without speaking to your prescriber first.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
What to Expect When Weaning Off
Many people experience appetite return within 1–2 weeks of stopping Mounjaro. This is a natural physiological response as the GIP and GLP-1 receptor agonist effects wear off. Weight regain is common — studies show some return of weight loss within weeks to months after stopping, though the amount varies significantly between individuals.
Side effect relief often happens quickly: nausea, stomach upset, and other gastrointestinal effects typically resolve within days or weeks. Your energy levels and appetite sensations should normalise gradually. Track your weight loss progress using our free progress tracker to monitor changes and share data with your GP.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Can I stop Mounjaro suddenly, or do I need to wean off gradually?
You should not stop suddenly. Abrupt cessation can cause rapid appetite return, blood sugar spikes (if diabetic), and significant weight regain. Always speak to your GP or prescriber about a safe step-down plan, which typically reduces your dose gradually over weeks rather than stopping at once.
How long does it take to wean off Mounjaro?
Weaning typically takes 4–12 weeks depending on your current dose. Your prescriber might step you down incrementally (e.g., 15 mg → 10 mg → 5 mg → stop) with at least 2–4 weeks at each lower dose. The pace is individualised based on your health, appetite return, and any side effects you experience.
Will I regain weight after stopping Mounjaro?
Weight regain is common after stopping. The amount and speed vary individually — some people regain weight within weeks, others more gradually. This is why maintaining diet and physical activity changes is crucial. Calculate your healthy weight range using our free BMI calculator to set realistic goals during this transition.
What happens to Mounjaro side effects when I wean off?
Most side effects improve quickly once you reduce your dose. Nausea, constipation, and stomach upset typically ease within days to weeks. However, appetite return can feel intense initially. Your GP can advise on managing this — sometimes smaller, more frequent meals help during the weaning phase.
Do I need blood tests or monitoring while stopping Mounjaro?
Yes. Your GP may recommend monitoring, especially if you have type 2 diabetes or other health conditions. Blood sugar levels, weight, and appetite should be tracked throughout the weaning process. You may need adjustments to other medications as your metabolism and glucose control change.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.