The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
Free tracker included with every download this week
Is Mounjaro Going Up — Understanding Dose Titration
If you're asking "is Mounjaro going up?", you're likely referring to dose titration — the gradual increase in your injection dose over time. Mounjaro (tirzepatide) is prescribed starting at a low dose, then increased every 4 weeks to find the dose that works best for you. This is a normal part of the treatment plan, designed to help your body adjust while maximising effectiveness. Your prescriber will guide you through each stage, and you can use our free GLP-1 weight loss calculator to help understand potential results at different doses.
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Calculate Your BMI Instantly
Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
How Mounjaro Dose Titration Works
Mounjaro dose titration is a structured progression that starts low and increases gradually. Your treatment plan will follow this schedule:
- Weeks 1–4: 2.5 mg once weekly (starting dose)
- Weeks 5–8: 5 mg once weekly
- Weeks 9–12: 7.5 mg once weekly
- Weeks 13–16: 10 mg once weekly
- Weeks 17–20: 12.5 mg once weekly
- Week 21+: 15 mg once weekly (maximum dose)
You must stay on each dose for at least 4 weeks before increasing. Your prescriber may keep you at a lower dose if you experience side effects or if that dose is working well for you. Never increase your dose yourself — your prescriber will instruct you when to go up. Each Mounjaro KwikPen contains 4 doses for 4 weeks, so you'll receive a new prescription when it's time to progress.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
Why Doses Increase and When to Stop
Doses increase gradually because your body needs time to adapt to the medication. Starting low reduces side effects like nausea and digestive discomfort. As your body adjusts, a higher dose may improve appetite control and support better weight loss results. However, you don't always go all the way to 15 mg. Many people find their optimal dose at 5 mg, 10 mg, or 12.5 mg and stay there long-term. If you experience persistent side effects at a higher dose, your prescriber may recommend staying at your current dose or even stepping down. The goal is finding the dose that balances effectiveness with tolerability for your individual body. Your GP or prescriber will monitor your progress and adjust your plan as needed.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Will my Mounjaro dose definitely go up every 4 weeks?
No. While the standard plan increases every 4 weeks, your prescriber may pause at any dose if it's working well for you or if you experience side effects. Some people reach their optimal dose at 5 mg or 10 mg and remain there. Dose progression is individualised based on your response and tolerance.
What's the maximum Mounjaro dose I can take?
The maximum licensed dose is 15 mg once weekly. However, many people achieve good results at lower doses like 10 mg or 12.5 mg. Your prescriber will not push you beyond a dose you're tolerating well.
What if I experience side effects when my dose goes up?
Tell your prescriber immediately. Common side effects (nausea, constipation, diarrhoea) often improve within a few days as your body adapts. If they persist, your prescriber may recommend staying at your current dose longer or stepping down to a lower dose.
How does Mounjaro dose compare to Wegovy dose?
Mounjaro (tirzepatide) is a dual GIP and GLP-1 agonist with a maximum dose of 15 mg weekly, whilst Wegovy (semaglutide) is a GLP-1 agonist with a maximum dose of 2.4 mg weekly. The doses are not directly comparable — they work through different mechanisms and concentrations.
Can I stay on a lower Mounjaro dose long-term, or must I keep increasing?
You can stay on any dose long-term if it's working for you and you're tolerating it well. Many people maintain at 10 mg or 12.5 mg indefinitely. The goal is finding your optimal dose, not reaching the maximum — your prescriber will advise what's right for you.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.