The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
Free tracker included with every download this week
Why Are My Mounjaro Cravings Coming Back?
If food cravings are returning while taking Mounjaro, you're not alone — and there are several explanations. Mounjaro (tirzepatide) works by activating GLP-1 and GIP hormone pathways to reduce appetite, but this effect can plateau over time, your dose may need adjustment, or your body may have adapted to the medication. Understanding why this happens and what your options are can help you maintain your weight loss progress. Your GP or prescriber can assess whether a dose increase, lifestyle adjustment, or alternative approach is right for you.
10,000+ calculations today · NHS-aligned thresholds · 100% free
Calculate Your BMI Instantly
Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Why Appetite Control Fades and What Changes in Your Body
Mounjaro's appetite-suppressing effects work through two hormone pathways — GIP and GLP-1 — which signal fullness to your brain and slow gastric emptying. However, several factors can reduce this effect over time:
- Tolerance: Your body may become accustomed to the medication's effects, particularly the gastric slowing component, which often diminishes within weeks
- Dose plateau: If you're on your current maintenance dose (up to 15 mg weekly), you may need titration to the next level if your prescriber agrees this is appropriate
- Lifestyle drift: Gradual changes in eating habits or activity levels can reintroduce cravings even if the medication remains effective
- Hormonal factors: Stress, sleep deprivation, and menstrual cycle changes can increase hunger signals regardless of medication
Clinical experience shows that returning appetite is common and doesn't mean Mounjaro has stopped working — it often signals that dose adjustment or lifestyle reinforcement is needed.
Clinically BackedWeight Loss
No appointments. No waiting rooms. Just care — from a UK-regulated online pharmacy.
How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
Next Steps: What to Do When Cravings Return
If your Mounjaro cravings are coming back, your first step is to contact your prescriber or GP — they can review your current dose, assess your weight loss progress, and determine whether a dose increase is appropriate. If you're not yet on the maximum dose of 15 mg weekly, titration may help restore appetite suppression. Independently, reinforce your diet and exercise habits: keep a food diary, increase protein and fibre intake, stay hydrated, and move more. Our free GLP-1 weight loss calculator can help you track expected outcomes at different doses, while our BMI calculator and progress tracker help monitor your overall health trajectory. Remember that some appetite return is normal, and medication works best alongside consistent lifestyle changes.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Is it normal for Mounjaro's appetite suppression to wear off?
Yes. Clinical experience shows that appetite suppression can plateau after several months, particularly the gastric slowing effect. This doesn't mean Mounjaro isn't working — it often indicates your body has adapted or a dose adjustment may help. Your prescriber can assess whether increasing your dose is appropriate.
Can I increase my Mounjaro dose if cravings return?
Possibly, but only under prescriber guidance. Mounjaro starts at 2.5 mg and increases every 4 weeks up to a maximum of 15 mg weekly. If you're below 15 mg and your prescriber agrees, dose escalation may restore appetite control. Never adjust your dose without clinical advice.
What's the difference between Mounjaro and Wegovy if I'm experiencing appetite return?
Mounjaro (tirzepatide) is a dual GIP+GLP-1 agonist, whilst Wegovy (semaglutide) is a GLP-1-only agonist. Mounjaro may provide stronger initial appetite suppression, but both can show tolerance. If appetite returns on one, your prescriber might explore alternatives, but this requires individual clinical assessment.
Could my cravings be returning because of my lifestyle rather than the medication?
Absolutely. Even effective medications require consistent diet and exercise. Common triggers include skipped meals, insufficient protein, emotional eating, and reduced activity. Before assuming medication failure, review your eating patterns, sleep quality, and stress levels — and discuss findings with your GP.
What if increasing my Mounjaro dose doesn't help my cravings?
Your GP can explore several options: confirming you're following dietary guidance, investigating underlying hormonal changes, adjusting medication timing, or considering alternative medications like Wegovy. Don't assume the medication has failed — your prescriber can run tests and create a revised plan together.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.