The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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Mounjaro Hoarse Voice vs Wegovy — What's the Difference?
Hoarse voice is not a common side effect listed for either Mounjaro (tirzepatide) or Wegovy (semaglutide), but both weight loss injections can cause nausea, vomiting, and gastrointestinal changes that may indirectly affect your voice or throat. This UK health guide compares how these two prescription medications work, what the clinical trials actually showed about side effects, and how your GP or prescriber will assess which is more suitable for you based on your individual health.
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Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Mounjaro vs Wegovy — Mechanism, Trials, and Reported Side Effects
Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist — it activates two natural hormone pathways that work together to regulate appetite and blood sugar. Wegovy (semaglutide) is a GLP-1 receptor agonist only, meaning it activates a single hormone pathway. Both are prescription-only weight management injections available in the UK following clinical assessment.
In the SURMOUNT-1 clinical trial for Mounjaro, the most common side effects at the maximum 15 mg dose were nausea (25.3%), diarrhoea (22.7%), and vomiting (11%). In the STEP-1 trial for Wegovy at 2.4 mg, nausea affected approximately 25%, diarrhoea 20.5%, and vomiting 6.8%. Neither trial specifically listed hoarse voice as a frequent adverse event. However, persistent nausea or vomiting — both common with these medications — can theoretically affect throat tissue over time, though this is not established as a direct side effect.
Use our GLP-1 weight loss calculator to explore potential outcomes with each medication, and discuss throat or voice concerns with your prescriber before starting treatment.
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If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
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Individual Suitability — How Your Prescriber Will Decide
Neither Mounjaro nor Wegovy is "better" for preventing hoarse voice — hoarse voice is simply not a recognised side effect of either medication based on clinical trial data. Your GP or prescriber will choose between them based on your BMI, weight-related health conditions, other medications, medical history, and personal preference.
Both require a BMI of 30 kg/m² or above, or 27 kg/m² with weight-related conditions (lower thresholds for South Asian, Chinese, Black African, or Caribbean heritage). Both are prescription-only and available through NHS specialist services or private online prescribing. If you have existing voice or throat concerns, mention these during your clinical assessment — your prescriber can discuss the actual risks and monitor you during treatment. Use our BMI calculator to check your starting point, and book an appointment with your GP to discuss which medication suits your health profile.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Is hoarse voice a known side effect of Mounjaro or Wegovy?
Hoarse voice is not listed as a common or frequent side effect of either medication in clinical trials. However, both can cause nausea and vomiting, which may irritate the throat indirectly. If you experience persistent hoarse voice during treatment, contact your GP or prescriber to report it and rule out other causes.
Which medication causes fewer throat or voice problems — Mounjaro or Wegovy?
Neither medication has hoarse voice as a documented side effect. Gastrointestinal symptoms like nausea are more common than throat issues. If you have pre-existing voice or throat concerns, discuss these with your prescriber before starting either medication to plan appropriate monitoring.
What are the most common side effects of Mounjaro and Wegovy?
Both medications commonly cause nausea, diarrhoea, constipation, and stomach pain, especially in the first few weeks. These usually improve over time as your body adjusts. Mounjaro and Wegovy side effects are similar because both work on appetite-regulating hormones; Mounjaro's dual mechanism may cause slightly different patterns, but hoarse voice is not a typical concern for either.
Can I switch from Mounjaro to Wegovy if I develop throat problems?
If you experience throat issues on one medication, your prescriber may consider switching you to the other — though hoarse voice itself is unlikely to be the cause since it's not a recognised side effect. Switching between GLP-1 medications requires prescriber guidance and should not be done without consultation.
How do I know if I'm eligible for Mounjaro or Wegovy on the NHS?
You need a BMI of 30 kg/m² or above, or 27 kg/m² with weight-related conditions like type 2 diabetes or high blood pressure. Use our free BMI calculator to check your starting point, then discuss prescription weight management options with your GP. Access is through NHS specialist tier 3 services, though waiting lists vary by region.
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