The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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What Are The Maintenance Doses Of Mounjaro?
Mounjaro (tirzepatide) has five maintenance dose options in the UK, ranging from 5 mg to 15 mg once weekly. After starting at 2.5 mg, your prescriber will gradually increase your dose over 16–20 weeks, with each maintenance dose held for a minimum of 4 weeks before escalation. This guide explains how Mounjaro dose titration works in UK practice, which maintenance dose is most commonly used, and how to discuss your personal maintenance dose with your GP or specialist.
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What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Mounjaro Maintenance Doses And Titration Schedule
Mounjaro is supplied as once-weekly injections in a KwikPen device, with each pen containing four doses (a four-week supply). The maintenance doses available in the UK are:
- 5 mg once weekly — first standard maintenance dose after initial titration
- 7.5 mg once weekly — escalation option if needed
- 10 mg once weekly — mid-range maintenance dose
- 12.5 mg once weekly — escalation option if needed
- 15 mg once weekly — maximum licensed dose
Your prescriber will start you on 2.5 mg for the first four weeks, then increase by 2.5 mg every four weeks until reaching your optimal maintenance dose. Most people reach their maintenance dose within 16–20 weeks. The SURMOUNT clinical trials showed that the 15 mg maintenance dose produced average weight loss of approximately 21% body weight, though individual results vary significantly. You remain on your chosen maintenance dose as long as the medication continues to be prescribed and is beneficial for you.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
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Maintenance Doses In NHS And Private UK Settings
In NHS specialist tier 3 weight management services, the dose choice is individualised based on your response, tolerability, and health conditions. Some patients reach therapeutic benefit at 5 mg or 10 mg and do not require further escalation. NHS prescribers follow NICE guidance and MHRA safety monitoring closely. In private UK settings, the same dose range applies, and your prescriber will assess which maintenance dose is right for you following your online consultation. Our free GLP-1 weight loss calculator can help you explore potential outcomes at different maintenance doses. Regardless of setting, changing or stopping your maintenance dose should always be discussed with your prescriber — never adjust doses independently.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
What is the most common Mounjaro maintenance dose used in the UK?
The 10 mg maintenance dose is widely used, though there is no single "standard" dose. NHS prescribers individualise the choice based on your response and tolerability. Some patients achieve their goals at 5 mg, while others require 15 mg. Your prescriber will assess what works best for you.
How long does it take to reach a maintenance dose of Mounjaro?
It typically takes 16–20 weeks to reach your target maintenance dose, as your prescriber increases by 2.5 mg every four weeks starting from the initial 2.5 mg. Each dose is held for a minimum of four weeks before escalation to allow your body to adjust.
Can you stay on a Mounjaro maintenance dose indefinitely?
Yes, you can continue your maintenance dose as long as your prescriber considers it beneficial and you continue to tolerate it well. If you wish to stop or change your dose, always discuss this with your GP or prescriber first — do not adjust independently.
Is there a difference between NHS and private Mounjaro maintenance doses in the UK?
No, the dose range is the same (5 mg to 15 mg weekly). Both NHS and private prescribers use the same MHRA-approved dosing schedule. The difference is in access route and waiting times, not in the medication itself or available doses.
What does the SURMOUNT trial tell us about Mounjaro maintenance doses?
The SURMOUNT-1 trial showed average weight loss of approximately 15% at 5 mg, 19.5% at 10 mg, and 20.9% at 15 mg over 72 weeks. However, individual results vary considerably, and higher doses do not assures proportionally greater weight loss for every person.
Ready to take control of your weight loss journey?
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