The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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No Suppression On Mounjaro — What This Means
If you're not experiencing appetite suppression on Mounjaro, you're not alone — some people notice less appetite reduction than expected, especially in the early weeks or at lower doses. This guide explains why this happens, what you can do about it, and the UK cost and access routes for tirzepatide (Mounjaro). Whether you're considering NHS access or private prescription, we'll walk you through your options, typical costs, and how the process works in the UK.
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Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Understanding Appetite Suppression & Dose Response
Appetite suppression on Mounjaro (tirzepatide) is not immediate or assured for everyone. Some people experience strong appetite reduction within days; others notice gradual changes over weeks. Several factors affect how much suppression you feel:
- Dose level: Lower doses (2.5 mg to 5 mg) may cause less noticeable suppression than higher doses (10 mg to 15 mg)
- Individual variation: Genetics, metabolism, and baseline eating habits influence your response
- Timeline: Suppression often strengthens as your dose increases during the titration schedule (minimum 4 weeks per dose)
- Stomach adaptation: Your digestive system may adjust over time, reducing the "slowing" effect that helps suppress appetite
If you're on a lower dose and not feeling suppression, your prescriber may recommend continuing the dose titration schedule to reach a higher maintenance dose where effects are typically more pronounced. Clinical trials showed stronger weight loss results at the maximum 15 mg dose compared to early-phase doses.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
NHS vs Private: Cost, Access & How to Get Mounjaro in the UK
NHS access: Mounjaro is approved by NICE for specialist tier 3/4 weight management services. You'll need a referral from your GP, but availability varies significantly by region (ICB). Waiting lists can be long — sometimes months or years. Once approved, it's typically free on the NHS.
Private prescription route: You can access Mounjaro through a UK-licensed online prescriber without an NHS referral. An online clinical assessment takes 10–20 minutes, and if approved, your prescription is sent to a GPhC-registered pharmacy. Costs range from approximately £140–£280 per month depending on dose and provider. The Mounjaro KwikPen (pre-filled injection device) is dispensed directly to you.
Both routes require a prescription and clinical suitability assessment — Mounjaro is not available over-the-counter. Your prescriber will check your BMI (typically 30+, or 27+ with weight-related health conditions), medical history, and current medications before approving it.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Why am I not feeling appetite suppression on Mounjaro?
Appetite suppression varies between individuals. Lower doses (2.5–5 mg) typically cause less noticeable suppression than higher doses. You may also be in the early adaptation phase — suppression often increases as you progress through the dose titration schedule. Continuing to your target dose usually results in stronger effects. Some people also experience less stomach-slowing as their body adapts over time.
How much does Mounjaro cost privately in the UK?
Private Mounjaro costs range from approximately £140–£280 per month depending on your dose and the provider. A starter dose (2.5 mg) is typically cheaper than maximum doses (15 mg). This is the medication cost only — clinical consultation fees vary by provider but are usually £20–£50. Always check the full cost upfront before committing.
Can I get Mounjaro free on the NHS?
Mounjaro is approved by NICE for NHS specialist weight management services (tier 3/4), so it can be free if prescribed through your GP's referral pathway. However, NHS availability is limited by region and waiting lists can be very long — sometimes over a year. Private prescription access is typically faster but involves costs. Ask your GP about your local NHS tier 3 services and estimated waiting times.
What's the difference between Mounjaro and Wegovy in the UK?
Both are once-weekly weight loss injections available in the UK through NHS or private prescription. Mounjaro (tirzepatide) is a dual GIP and GLP-1 receptor agonist with a maximum dose of 15 mg. Wegovy (semaglutide) is a GLP-1 agonist only, with a maximum dose of 2.4 mg. Clinical trials suggest Mounjaro may produce slightly higher average weight loss, but individual results vary significantly.
Do I need a GP referral to get a private Mounjaro prescription?
No — you can access Mounjaro through a private online prescriber without a GP referral. You'll complete a brief online clinical assessment, and if approved, a UK-licensed prescriber will issue a prescription to a GPhC-registered pharmacy. However, it's still worth informing your GP that you're considering or using a weight loss injection so they can monitor your health and adjust any other medications if needed.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.