The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
Free tracker included with every download this week
Can You Take Pregabalin With Mounjaro?
Pregabalin (Lyrica) and Mounjaro (tirzepatide) can typically be taken together, but it's essential to inform your prescriber about all medications you're taking before starting Mounjaro. Both drugs work through different mechanisms and do not have a known direct interaction. However, individual factors like your health conditions, kidney function, and other medicines may affect safety. Your GP or prescriber will assess your specific situation during a clinical consultation.
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Calculate Your BMI Instantly
Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
How Mounjaro and Pregabalin Work Differently
Mounjaro is a dual GIP and GLP-1 receptor agonist — a once-weekly injection licensed in the UK for weight management. It works on appetite regulation and blood sugar control in the gut and brain. Pregabalin, by contrast, is a nerve pain medication that affects neurotransmitters in the central nervous system to reduce pain and anxiety. Because they act on completely different body systems, there is no established drug interaction between them. However, Mounjaro is prescription-only and requires a clinical assessment to ensure it is suitable for you. Your prescriber will review your full medical history, including any existing medications like pregabalin, before issuing a prescription via the Mounjaro KwikPen delivery system.
Clinically BackedWeight Loss
No appointments. No waiting rooms. Just care — from a UK-regulated online pharmacy.
How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
What You Must Tell Your Prescriber
Before starting Mounjaro, inform your healthcare provider that you take pregabalin — even though there is no direct interaction. This allows your prescriber to assess whether Mounjaro is appropriate for your individual health profile. Be prepared to discuss:
- Your pregabalin dose and what it treats (neuropathic pain, anxiety, epilepsy)
- Any other medications or supplements you take
- Your kidney or liver function
- Any history of pancreatitis, gallbladder problems, or thyroid cancer
- Whether you are pregnant, planning pregnancy, or breastfeeding
Your GP can refer you to an NHS specialist weight management service, or you can access Mounjaro privately through a GPhC-registered online prescriber following an online clinical assessment.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Is it safe to take pregabalin and Mounjaro together?
Yes, pregabalin and Mounjaro can typically be taken together as there is no known direct drug interaction between them. However, safety depends on your individual health circumstances. Always inform your prescriber about all medications, including pregabalin, before starting Mounjaro. Your prescriber will assess your full medical history to confirm Mounjaro is appropriate for you.
Will pregabalin affect how Mounjaro works?
No — pregabalin does not affect the mechanism of action of Mounjaro. Mounjaro works on GIP and GLP-1 receptors in the gut and brain, whilst pregabalin affects nerve pain signalling. They work through entirely different pathways, so pregabalin is unlikely to reduce Mounjaro's effectiveness.
What should I tell my prescriber about taking pregabalin?
Tell your prescriber the pregabalin dose, how long you have been taking it, and what condition it treats (such as neuropathic pain, anxiety, or epilepsy). This information helps them assess whether Mounjaro is appropriate for you and whether any dose adjustments to your existing medications are needed.
Can I start Mounjaro if I take pregabalin?
Most people taking pregabalin can start Mounjaro, but your individual health profile must be assessed first. A UK-licensed prescriber will evaluate your medical history, current medications, kidney and liver function, and any contraindications before prescribing. You can access assessment through NHS tier 3 specialist services or privately through an online prescriber.
Do I need to change my pregabalin dose when starting Mounjaro?
Unlikely — but only your GP or specialist can advise. Mounjaro does not typically interact with pregabalin, so your pregabalin dose would not usually change. However, if you experience any new symptoms or side effects after starting Mounjaro, contact your GP immediately.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.