The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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Semaglutide Weight Loss Dosage Chart — Wegovy ML Doses
Wegovy (semaglutide) is a prescription-only once-weekly weight loss injection licensed in the UK. The medication comes in five dose strengths, escalated over several weeks to allow your body to adjust and minimise side effects. This guide shows the exact semaglutide dosage chart in millilitres, the timing between dose increases, and what to expect at each stage. Wegovy is a GLP-1 receptor agonist that works by reducing appetite and helping you feel fuller after smaller meals. Individual results vary significantly, and a prescriber will assess whether this medication is suitable for you following a clinical assessment.
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Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Complete Semaglutide Dosage Chart — All Wegovy Doses in ML
Wegovy semaglutide dosing schedule: The medication is escalated gradually over approximately 16 weeks to reach the maximum maintenance dose of 2.4 mg once weekly. Each pre-filled pen contains one dose and is injected under the skin (subcutaneously) once per week, on the same day each week.
- 0.25 mg (0.25 ml) — Weeks 1–4 (starting dose)
- 0.5 mg (0.5 ml) — Weeks 5–8 (first escalation)
- 1 mg (1 ml) — Weeks 9–12 (second escalation)
- 1.7 mg (1.7 ml) — Weeks 13–16 (third escalation)
- 2.4 mg (2.4 ml) — Week 17 onwards (maintenance/maximum dose)
In clinical trials (STEP studies), participants on 2.4 mg semaglutide lost an average of approximately 15% of their body weight over 68 weeks, alongside a reduced-calorie diet and increased physical activity. However, weight loss varies between individuals. You can estimate your potential weight loss using our GLP-1 weight loss calculator, and track your progress with our free progress tracker as you progress through the escalation schedule.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
Important Dosing Information — What You Need to Know
Minimum time between doses: Always wait at least 7 days (one week) between injections. If you miss a dose, take it within 5 days of the scheduled day to stay on track. After 5 days, skip that dose and resume your normal weekly schedule.
Storage and preparation: Unopened pens must be refrigerated at 2–8°C and kept in their original carton. Once you start using a pen, it can be stored at room temperature (below 30°C) for up to 30 days before disposal. Always check the label for your exact dose in milligrams and ml before injecting, and rotate your injection sites (stomach, thigh, or upper arm) each week. Your prescriber or pharmacist will provide full injection training.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
What's the difference between Wegovy and Ozempic semaglutide dosing?
Both contain semaglutide, but Ozempic is licensed for type 2 diabetes (doses up to 2 mg) and is not approved for weight loss in the UK. Wegovy is the licensed weight management version, dosed up to 2.4 mg once weekly specifically for weight loss. Never switch between them without prescriber guidance — they have different licensed purposes.
Why is semaglutide weight loss dosage escalated slowly over weeks?
Gradual escalation allows your body to adjust and reduces side effects like nausea and stomach upset. Starting at 0.25 mg and increasing every 4 weeks helps your system adapt to the medication. If you experience side effects at a particular dose, your prescriber may extend the time at that dose before increasing further.
Can I skip doses or pause my semaglutide treatment?
You can pause treatment if needed, but stopping suddenly or skipping doses may reduce effectiveness and increase side effect risk when restarting. Always discuss any changes with your prescriber. If you miss a dose by more than 5 days, skip it and resume your normal weekly schedule — never take a double dose.
How long does a single semaglutide 2.4 mg injection last?
Each 2.4 mg injection lasts exactly one week (7 days). You inject once weekly on the same day. Each pre-filled pen contains one 2.4 ml dose. A standard prescription for maintenance typically provides 4 pens per month, covering 4 weekly injections.
Is semaglutide weight loss dosage the same for everyone?
No. Your prescriber may maintain you on a lower dose (0.5 mg, 1 mg, or 1.7 mg) if you experience side effects or respond well to a lower dose. The 2.4 mg dose is the maximum, but not everyone requires or tolerates the highest dose. Your prescriber will personalise your dosing based on your individual response and tolerance. Use our BMI calculator to establish your baseline, and track your progress throughout your treatment.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.