The UK's most complete GLP-1 guide
Every Question Answered. Every Side Effect Explained.
- How GLP-1 medications work
- Mounjaro vs Wegovy compared
- Injection instructions
- Side effects & solutions
- What to eat on treatment
- FAQs answered
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Should I Go Up To 7.5 Mounjaro?
Whether to increase your Mounjaro dose from 5mg to 7.5mg is a decision your prescriber will guide, based on your individual response, tolerance, and health goals. This page explains what the 7.5mg step means, what clinical evidence shows, and the key factors your GP or prescriber considers when recommending a dose increase. Use our free GLP-1 weight loss calculator to explore how different Mounjaro doses may impact projected outcomes, and remember that individual results vary significantly.
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Calculate Your BMI Instantly
Enter your height and weight below. Supports both imperial (stone & lbs) and metric (kg). Results include NHS category, healthy weight range, and ethnicity adjustments.
What Is BMI and Why Does It Matter?
Body Mass Index (BMI) is the most widely used screening tool for assessing whether your weight falls within a healthy range. Used by the NHS, GPs, and weight management services across the UK, BMI provides a quick snapshot of your weight relative to your height. The formula is simple: your weight in kilograms divided by your height in metres squared (kg/m²).
While BMI isn't a perfect measure — it doesn't account for muscle mass, bone density, or fat distribution — it remains the standard first step in identifying potential weight-related health risks including type 2 diabetes, cardiovascular disease, high blood pressure, and certain cancers.
The NHS also recommends adjusted thresholds for people of South Asian, Chinese, or Black African heritage — a BMI of 23 or above is classified as overweight, and 27.5 as obese. Our calculator includes this adjustment as a one-click toggle.
Understanding Mounjaro Dose Escalation
Mounjaro (tirzepatide) is a prescription-only weight management injection that works by activating dual GIP and GLP-1 hormone pathways. The standard titration schedule involves starting at 2.5mg and increasing by 2.5mg every 4 weeks, provided you tolerate each dose well. At 7.5mg, you're at the mid-range of the licensed dose scale (which goes up to 15mg maximum). Clinical data from the SURMOUNT-1 trial showed that higher doses tend to produce greater average weight loss — approximately 15% at 5mg, rising to around 20.9% at the maximum 15mg dose — though individual results vary considerably.
Your prescriber will consider: whether you've tolerated the 5mg dose without intolerable side effects, whether your weight loss progress has plateaued, your current BMI and health status, and whether 7.5mg is the next logical step in your plan. Dose increases are never mandatory — some people achieve excellent results and feel well at 5mg and choose to stay there.
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How It Works
Three simple steps to understand your weight and take action.
Enter your height and weight in our free calculator. Get your BMI, NHS category, healthy weight range, and ethnicity-adjusted thresholds instantly.
If your BMI suggests you're overweight or obese, explore our GLP-1 calculators to project potential weight loss on Mounjaro or Wegovy.
Use our progress tracker to log your weight weekly, visualise your journey with charts, and stay motivated — all stored privately in your browser.
Free Weight Loss Tools & Guides
Everything you need to understand your weight, explore medication options, and track your progress — completely free.
Key Factors Before Increasing Your Dose
Side effects at current dose: If you're experiencing significant nausea, vomiting, or stomach discomfort at 5mg, increasing to 7.5mg may worsen these effects initially. Discuss with your prescriber — sometimes staying at 5mg or taking time to adjust is the right choice.
Weight loss progress: If you've lost weight steadily on 5mg and feel satisfied, there's no clinical requirement to escalate. Your GP may recommend staying at your current dose long-term.
Individual tolerance: Some people feel excellent at 5mg and want to try higher doses; others find 5mg is their optimal balance. There's no universal "right" dose — it's about what works for your body and life.
Always discuss any dose change with your prescriber before adjusting. Use our GLP-1 weight loss calculator to model different dose scenarios and track your progress with our free progress tracker.
- Dual GIP/GLP-1 receptor agonist
- Up to 22.5% body weight loss (SURMOUNT-1)
- Weekly injection, dose escalation over 20+ weeks
- Available via private prescription in the UK
- Doses: 2.5mg → 5mg → 7.5mg → 10mg → 12.5mg → 15mg
- GLP-1 receptor agonist
- Up to 15–17% body weight loss (STEP trials)
- Weekly injection, 5-step dose escalation
- NHS & private prescription available
- Doses: 0.25mg → 0.5mg → 1mg → 1.7mg → 2.4mg
Mounjaro vs Wegovy: Head-to-Head
A side-by-side comparison of the two most popular GLP-1 weight loss medications available in the UK.
| Feature | Mounjaro | Wegovy |
|---|---|---|
| Drug class | Dual GIP/GLP-1 agonist | GLP-1 agonist |
| Active ingredient | Tirzepatide | Semaglutide |
| Avg. weight loss | 15–22.5% | 12–17% |
| Key trial | SURMOUNT-1 (2022) | STEP 1 (2021) |
| Max dose | 15 mg weekly | 2.4 mg weekly |
| Escalation period | 20–32 weeks | 16–20 weeks |
| Administration | Weekly injection (pen) | Weekly injection (pen) |
| NHS availability | Private prescription only | NHS & private |
| Approx. private cost | £150–£250/month | £150–£300/month |
| Common side effects | Nausea, diarrhoea, constipation | Nausea, vomiting, diarrhoea |
Data sourced from SURMOUNT-1 and STEP 1 clinical trials. Costs are approximate and vary by provider. Always consult a prescriber.
Am I Eligible for Weight Loss Medication?
In the UK, eligibility for GLP-1 weight loss medications like Mounjaro and Wegovy is based on your BMI and overall health profile.
- BMI of 30 or above (obese)
- Age 18 or over
- No contraindicated conditions
- Committed to lifestyle changes
- BMI of 27 or above
- Plus type 2 diabetes
- Or high blood pressure
- Or obstructive sleep apnoea
Use our BMI calculator to check whether your BMI falls within the eligible range.
How We Built These Tools
Every calculator and guide on myweightcheck is built with accuracy and transparency in mind. Our BMI calculator uses the standard WHO formula with NHS-aligned category thresholds. Our GLP-1 projections are modelled on published clinical trial data from SURMOUNT and STEP studies.
All data stays on your device. We don't require sign-ups, and we don't store your health information on any server. Your progress tracker saves data locally in your browser using localStorage, so only you can see it.
We're based in the UK and our tools are designed specifically for UK users — supporting stone & lbs by default, referencing NHS guidelines, using NICE-approved medication data, and linking to GPhC-registered pharmacies.
Frequently Asked Questions
Common questions about BMI, weight loss medications, and our free UK tools.
Is 7.5mg Mounjaro significantly more effective than 5mg?
Clinical trials showed dose-dependent weight loss — higher doses produced greater average loss. However, the difference between 5mg and 7.5mg is modest for many people, and individual variation is high. Your prescriber will assess whether stepping up aligns with your progress and tolerance.
What are the likely side effects of moving from 5mg to 7.5mg?
You may experience temporary nausea, diarrhoea, or constipation as your body adjusts, similar to when you first started Mounjaro. These often ease within a few days. If side effects were already problematic at 5mg, discuss this with your prescriber before increasing.
How long should I stay on 5mg before going up to 7.5mg?
NHS and clinical guidance recommend a minimum of 4 weeks on each dose to assess tolerance and efficacy. Your prescriber will advise based on your individual response. Never increase doses without clinical guidance.
Can I request to stay on 5mg if it's working well?
Yes, absolutely. If you're losing weight consistently, tolerating the dose well, and feel good, there's no medical reason to increase. Your prescriber can recommend staying at 5mg long-term or increasing later if progress slows.
What's the difference between Mounjaro and Wegovy if I'm considering alternatives?
Both are prescription-only weight management injections. Mounjaro (tirzepatide) uses dual GIP+GLP-1 action and reaches 15mg maximum. Wegovy (semaglutide) is a single GLP-1 agonist reaching 2.4mg. Clinical trials showed similar average weight loss (~15%), but individual response differs. Your prescriber will advise which suits you.
Ready to take control of your weight loss journey?
Start with a free BMI check, explore your GLP-1 options, or begin tracking your progress today. No sign-up. No cost. Just results.